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- Validation and discovery of natural products useful for the treatments of:
- diabetes and metabolic syndrome
- inflammation
- rheumatoid arthritis
- leishmaniasis
- malaria
- cancer
- Alzheimer's
- anti-viral (HIV, etc.)
- sickle cell anemia
- health and nutrition
- Toxin mechanism of action and identification of peptide and/or small molecule inhibitors
- Extraction, Screening, and bioprospecting methodology development:
- Screens-to-Nature (field-deployable initial screens for whole plant extracts)
- Botanical accuracy, biodocumentation and vouchering practices
- C. elegans, Arabidopsis, Drosophila, Saccharomyces cerevisiae and rodent model systems for toxicity screening
- Cell lines, e.g. SKOV, Vero cells and macrophages
- Bioavailability and metabolism
- Metabolite biomarkers, metabolite bioactivities
- Development of sustainable agricultural and collection practices for medicinal plants